b'AnarticlepublishedinJanuary 2007 in the journal CNS Spectrums by Dr. Young from Duke University suggested that safe levels of CoQ10 arebetween300mgto2,400mga day.Implications That Reduce Its EffectivenessCoQ10supplementationisnot yetwidelyprescribedinclinical practice. It is a nutraceutical rather thanapatentabledrug.Whenthis is the case, there appears a vacuum of knowledge and comprehension of the critical role that CoQ10 plays in multiplediseaseconditionsandan ignorance of the detrimental effects associatedwithCoQ10deficiency. This gap can be bridged by sharing this article with your physician for him or her to read and for him or her adramaticimprovementinheartSafety and Precautions to find the most applicable research, function, and he no longer requiredCoQ10isverysafeforhealthywhich at last look had some 16,430 any diuretics. By January of 2007, hisindividuals. However, if you are onsearch results for CoQ10 on PubMed improvement was great enough thatdiabeticmedications,diuretics,in- alone.he became quite active and requiredsulin,ACEinhibitors,betablock- A deficiency of CoQ10 can pro-no further hospitalizations. The caseers, calcium channel blockers, HMGduceahostofdiseaseconditions study ended with the physician stat- Co-Areductaseinhibitors,anti- throughout the body. This can occur ing: This single case represents verycoagulants,ordopamine-enhanc- inallagegroups,producingmany striking improvement that I have notingdrugs,checkwithyourdoctorvarietiesofdiseasefromepilepsy seen before in 25 years of cardiologyfirst. CoQ10s benefits may requireto cardiomyopathy, myopathy of all practice. We have now repeated andchangingdosagesofanyofthesesorts,toseizuresandmuchmore. are continuing to treat several otherdrugs. Also, check with your health- Statindrugs,forexample,reduce patientswithend-stageorfar-ad- care provider if you are pregnant orCoQ10levels,thusnecessitating vanced congestive heart failure withyou are giving this to a child. Lipidssupplementation. There are definite similar remarkable findings. (fats) are important for the uptakelinksbetweenstatinsandthemu-Thisstudydemonstratestheim- of CoQ10, similar to the uptake oftations in genes involved in CoQ10 portance of using ubiquinol, especial- Vitamin E. biosynthesis.Therefore,anyoneus-ly as we age. Keep in mind as well thatCoQ10 levels can be reduced bying statins should also be prescribed there is every indication that the long- certain foods, supplements or drugs,ubiquinol and ubiquinone. Through-known ubiquinone form has its ben- such as high amounts of fish oil andout the available literature one finds efitsapartfromthoseofubiquinol.especiallypharmaceuticalstatins.thatdietaryCoQ10supplementa-To take full advantage of the benefitsYou should check with your health- tion is the only available treatment of CoQ10, the dosage should includecare provider regarding the dosage.for deficiencies that require a rapid both forms and then each according toIt could go as high as 2,000 mg ofand distinct diagnosis.age as to which one you take the most.ubiquinone or a smaller amount ofStay healthy and support the Na-Also, as demonstrated, ubiquinolubiquinol.However,thestandardtionalHealthFederationsrelent-doesnotrequirethehighamountdosage appears to be recommendedless efforts to educate and promote neededbyubiquinonetogainthein the literature as 200 mg, with 100healthalternativeswhileprotecting sametherapeuticeffectforcertainmgofthatamountbeingubiqui- health freedom and free choice.conditions. none to gain the benefits of both. 18 H ealtHF reedomN ews /F all2022NHF_40-3_Linda_11-25-2022.indd 18 11/25/22 8:02 AM'